Evidence of Autoinduction Heterogeneity via Expression of the Agr System of Listeria monocytogenes at the Single-Cell Level

Author:

Garmyn Dominique12,Gal Laurent23,Briandet Romain45,Guilbaud Morgan45,Lemaître Jean-Paul12,Hartmann Alain12,Piveteau Pascal12

Affiliation:

1. Université de Bourgogne, UMR 1229, F-21000 Dijon, France

2. INRA, UMR 1229, F-21065 Dijon, France

3. AgroSup Dijon, F-21000 Dijon, France

4. INRA, UMR 1319 MICALIS, F-7835 Jouy-en-Josas, France

5. AgroParisTech, UMR 1319 MICALIS, F-9130 Massy, France

Abstract

ABSTRACT To investigate if the primary function of the Agr system of Listeria monocytogenes is to monitor cell density, we followed Agr expression in batch cultures, in which the autoinducer concentration was uniform, and in biofilms. Expression was heterogeneous, suggesting that the primary function of Agr is not to monitor population density.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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