Innate Antiviral Cytokine Response to Swine Influenza Virus by Swine Respiratory Epithelial Cells

Author:

Bakre Abhijeet A.1ORCID,Jones Les P.1,Murray Jackelyn1,Reneer Z. Beau1ORCID,Meliopoulos Victoria A.2ORCID,Cherry Sean2,Schultz-Cherry Stacey2ORCID,Tripp Ralph A.1ORCID

Affiliation:

1. Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

2. Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis Tennessee

Abstract

Swine are considered intermediate hosts that have facilitated influenza virus reassortment events that have given rise pandemics or genetically related viruses have become established in swine. In this study, we examine the innate antiviral response to swine influenza virus in primary and immortalized swine nasal and tracheal epithelial cells, and show virus strain- and host cell type-dependent differential expression of key interferons and interferon-stimulated genes.

Funder

American Lebanese Syrian Associated Charities

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference74 articles.

1. The evolution of seasonal influenza viruses

2. Continuing challenges in influenza

3. Knipe DM, Howley PM, Cohen JI, Griffin DE, Lamb RA, Martin MA, Racaniello VR, Roizman B (ed). 2013. Fields virology, 6th ed. Lippincott Williams & Wilkins, Philadelphia, PA.

4. Pathogenesis and Vaccination of Influenza A Virus in Swine

5. Swine as a Model for Influenza A Virus Infection and Immunity

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