Susceptibilities of 23 Desulfovibrio Isolates from Humans

Author:

Nakao Ken-ichi12,Tanaka Kaori2,Ichiishi Suguru2,Mikamo Hiroshige3,Shibata Toshiyuki1,Watanabe Kunitomo2

Affiliation:

1. Department of Oral and Maxillofacial Sciences, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan

2. Division of Anaerobe Research, Life Science Research Center, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan

3. Department of Infection Control and Prevention, Aichi Medical University, 21 Karimata, Yazako, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan

Abstract

ABSTRACT Antimicrobial susceptibilities of 23 strains of Desulfovibrio spp. were tested by Etest. Generally, Desulfovibrio spp. were highly susceptible to sulbactam-ampicillin, meropenem, clindamycin, metronidazole, and chloramphenicol: MIC 90 s of 6, 4, 0.19, 0.25, and 8 μg/ml, respectively. In addition, these strains generally showed high MICs to piperacillin and piperacillin-tazobactam. D esulfovibrio fairfieldensis (eight strains) was the species least susceptible to most agents, especially β-lactams, and was the only species resistant to fluoroquinolones. D esulfovibrio desulfuricans strain Essex 6 isolates were less susceptible to β-lactams than D. desulfuricans strain MB isolates.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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