Localization of Escherichia coli rpoC Mutations That Affect RNA Polymerase Assembly and Activity at High Temperature-Reference-Cited by-同舟云学术

Localization of Escherichia coli rpoC Mutations That Affect RNA Polymerase Assembly and Activity at High Temperature

Published:1999-04-15 Issue:8 Volume:181 Page:2663-2665
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Nedea Eduard C.¹,Markov Dmitriy¹²,Naryshkina Tatyana¹,Severinov Konstantin¹

Affiliation:

1. Waksman Institute and Department of Genetics, Rutgers, The State University, Piscataway, New Jersey 08854,1 and

2. Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia2

Abstract

ABSTRACT We localized five rpoC (β′) mutations affecting Escherichia coli RNA polymerase assembly. The Ts4, XH56, and R120 mutations changed β′ residues conserved throughout eubacteria; the JE10092 mutation occurred in the hypervariable region; rpoC1 (TsX) changed a universally conserved residue and corresponds to yeast rpb1-1 . Thus, distinct, predominantly conserved β′ residues participate in interactions holding RNA polymerase together.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.181.8.2663-2665.1999

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