Affiliation:
1. Department of Medicine, Medical Center of Delaware, Wilmington 19899.
Abstract
Agar dilution anaerobic susceptibility studies using rifampin, vancomycin, metronidazole, and bacitracin individually and in combination were performed with Clostridium difficile. Fifty-five strains of C. difficile were studied. Eighty-five percent of strains tested (29 of 34) were synergistically inhibited by the combination of bacitracin and rifampin (fractional inhibitory concentration, less than or equal to 0.50).
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference13 articles.
1. Therapy of relapsing Clostridium difficile-associated diarrhea with the combination of vancomycin and rifampin;Buggy B. P.;Clin. Gastroenterol.,1987
2. Cytotoxicity assay in antibiotic-associated colitis;Chang T. W.;J. Infect. Dis.,1979
3. Oral bacitracin vs vancomycin therapy for Clostridium difficile-induced diarrhea;Dudley M. P.;Arch. Intern. Med.,1986
4. Antagonists of nucleic acid derivatives. VIII. Synergism in combinations of biochemically related antimetabolites;Elion G. B.;J. Biol. Chem.,1953
5. Fekety R. 1985. Antibiotic-associated colitis p. 655-660. In G. L. Mandell R. G. Douglas Jr. and J. E. Bennett (ed.) Principles and practice of infectious diseases 2nd ed. John Wiley & Sons Inc. New York.
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