Evaluation of [ 13 C]Urea Breath Test and Helicobacter pylori Stool Antigen Test for Diagnosis of H. pylori Infection in Children from a Developing Country

Author:

Cardinali Luciana de Carvalho Costa1,Rocha Gifone Aguiar1,Rocha Andreia Maria Camargos1,de Moura Sílvia Beleza2,de Figueiredo Soares Taciana1,Esteves Ana Maria Braz1,Nogueira Ana Margarida Miguel Ferreira3,Cabral Mônica Maria Demas Álvares3,de Carvalho Anfrisina Sales Teles1,Bitencourt Paulo4,Ferreira Alexandre5,Queiroz Dulciene Maria Magalhães1

Affiliation:

1. Laboratory of Research in Bacteriology

2. Instituto de Ciências Biológicas, UFMG

3. Department of Pathology, Faculdade de Medicina

4. Hospital Felício Rocho

5. Hospital das Clínicas UFMG, Belo Horizonte, Brazil

Abstract

ABSTRACT The [ 13 C]urea breath test ( 13 C-UBT) and Helicobacter pylori stool antigen test (HpSA) for the diagnosis of H. pylori infection in children were validated. The sensitivity, specificity, and positive and negative predictive values were 93.8, 99.1, 97.8, and 98.0%, respectively, for the 13 C-UBT and 96.9, 100, 100, and 98.0%, respectively, for HpSA. Both tests are appropriate for diagnosing H. pylori infection in children.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference10 articles.

1. Bazzoli, F., L. Cecchini, L. Corvaglia, M. Dall' Antonia, C. De Giacomo, S. Fossi, L. G. Casali, S. Gullini, R. Lazzari, G. Leggeri, P. Lerro, V. Valdambrini, G. Mandrioli, M. Marani, P. Martelli, A. Miano, G. Nicolini, G. Oderda, P. Pazzi, P. Pozzato, L. Ricciardiello, E. Roda, P. Simoni, S. Sottili, G. Torre, L. Urso, and R. M. Zagari. 2000. Validation of the 13C-urea breath test for the diagnosis of Helicobacter pylori infection in children: a multicenter study. Am. J. Gastroenterol.95:646-650.

2. Bode, G., D. Rothenbacher, H. Brenner, and G. Adler. 1998. Variation in the 13C-urea breath test value by nationality in Helicobacter pylori-infected children. Scand. J. Gastroenterol.33:468-472.

3. Braden, B., H. Posselt, P. Ahrens, R. Kitz, C. F. Dietrich, and W. F. Caspary. 2000. New immunoassay in stool provides an accurate noninvasive diagnostic method for Helicobacter pylori screening in children. Pediatrics106:115-117.

4. Chang, M. C., Y. T. Chang, C. T. Sun, M. S. Wu, H. P. Wang, and J. T. Lin. 2002. Quantitative correlation of Helicobacter pylori stool antigen (HpSA) test with 13C-urea breath test (13C-UBT) by the updated Sydney grading system of gastritis. Hepatogastroenterology49:576-579.

5. Kato, S., K. Ozawa, M. Konno, H. Tajiri, N. Yoshimura, T. Shimizu, T. Fujisawas, D. Abukawa, T. Minoura, and K. Iiumuma. 2002. Diagnostic accuracy of the 13C-urea breath test for childhood Helicobacter pylori infection: a multicenter Japanese study. Am. J. Gastroenterol.97:1668-1673.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3