Povidone Iodine: Properties, Mechanisms of Action, and Role in Infection Control and Staphylococcus aureus Decolonization-Reference-Cited by-同舟云学术

Povidone Iodine: Properties, Mechanisms of Action, and Role in Infection Control and Staphylococcus aureus Decolonization

Published:2020-08-20 Issue:9 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Lepelletier Didier¹,Maillard Jean Yves²,Pozzetto Bruno³⁴,Simon Anne⁵

Affiliation:

1. Bacteriology/Hospital Hygiene Department, Nantes University Hospital, Nantes, France

2. School of Pharmacy and Pharmaceutical Sciences and Cardiff Institute for Tissue Engineering and Repair, Cardiff University, Cardiff, United Kingdom

3. GIMAP-EA3064, University of Saint-Etienne, Saint-Etienne, France

4. Department of Infectious Agents and Hygiene, Saint-Etienne University Hospital, Saint-Etienne, France

5. Pole de Microbiologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium

Abstract

Nasal decolonization is an integral part of the strategies used to control and prevent the spread of methicillin-resistant Staphylococcus aureus (MRSA) infections. The two most commonly used agents for decolonization are intranasal mupirocin 2% ointment and chlorhexidine wash, but the increasing emergence of resistance and treatment failure has underscored the need for alternative therapies. This article discusses povidone iodine (PVP-I) as an alternative decolonization agent and is based on literature reviewed during an expert’s workshop on resistance and MRSA decolonization.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00682-20

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5. Treatment of familial staphylococcal infection—comparison of mupirocin nasal ointment and chiorhexidine/neomycin (Naseptin) cream in eradication of nasal carriage

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