Local Regulator AcrR Regulates Persister Formation by Repression of AcrAB Efflux Pump during Exponential Growth in Aeromonas veronii-Reference-Cited by-同舟云学术

Local Regulator AcrR Regulates Persister Formation by Repression of AcrAB Efflux Pump during Exponential Growth in Aeromonas veronii

Published:2023-02-28 Issue: Volume: Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ma Xiang¹^ORCID,Hu Kang¹,Xiong Yuesheng¹,Li Hong¹,Li Juanjuan¹,Tang Yanqiong¹,Liu Zhu¹²

Affiliation:

1. School of Life Sciences, Hainan University, Haikou, China

2. One Health Institute, Hainan University, Haikou, China

Abstract

Bacterial persisters refer to a small fraction of dormant variants that survive treatment with high concentrations of antibiotics. Increasing research indicates that multidrug efflux pumps play a major role in persister formation in many Gram-negative organisms.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00969-22

Reference43 articles.

1. Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance

2. Antibiotic resistance and persistence—Implications for human health and treatment perspectives

3. Definitions and guidelines for research on antibiotic persistence

4. Evolutionary causes and consequences of bacterial antibiotic persistence

5. Toxin-antitoxin systems in bacterial growth arrest and persistence

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