Release of Shiga Toxin from Shigella dysenteriae 1 by Polymyxin B-Reference-Cited by-同舟云学术

Release of Shiga Toxin from Shigella dysenteriae 1 by Polymyxin B

Published:1983-04 Issue:1 Volume:40 Page:425-428
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Griffin Darrell E.¹,Gemski P.¹

Affiliation:

1. Department of Biological Chemistry, Walter Reed Army Institute of Research, Washington, D.C. 20012

Abstract

Release of Shiga toxin from Shigella dysenteriae 1 was found to occur after exposure to polymyxin B. The amount of toxin released was dependent on both the polymyxin concentration and time of incubation. An immunoblot characterization of the Shiga toxin released by polymyxin treatment demonstrated that it is electrophoretically similar to purified Shiga toxin and to Shiga toxin present in crude bacterial sonicates of S. dysenteriae 1 cells.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.40.1.425-428.1983

Reference19 articles.

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2. Inhibition of protein synthesis in intact HeLa cells by Shigella dysenteriae 1 toxin;Brown J. E.;Infect. Immun.,1980

3. Inhibition of protein synthesis by Shiga toxin;Brown J. E.;FEBS Lett.,1980

4. Differential release of periplasmic versus cytoplasmic enzymes from Escherichia coli B by polymyxin B;Cerny G.;Arch. Microbiol.,1971

5. Disc electrophoresis. II. Method and application to serum proteins;Davis B. J.;Ann. N. Y. Acad. Sci.,1964

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