Human Interferon-γ Enhances the Expression of Class I and Class II Major Histocompatibility Complex Products in Neoplastic Cells More Effectively than Interferon-α and Interferon-β-Reference-Cited by-同舟云学术

Human Interferon-γ Enhances the Expression of Class I and Class II Major Histocompatibility Complex Products in Neoplastic Cells More Effectively than Interferon-α and Interferon-β

Published:1983-04 Issue:1 Volume:40 Page:172-176
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Dolei Antonina¹²,Capobianchi Maria R.¹,Ameglio Franco³

Affiliation:

1. Istituto di Virologia, University of Rome, Rome, Italy

2. Cattedra di Patologia Generale, University of Camerino, Camerino, Italy

3. Laboratorio di Biologia Cellulare del Consiglio Nazionale delle Ricerche, Rome, Italy

Abstract

Human interferon-γ was more effective than interferon-β or -α in stimulating production of immunoassociated antigens; HLA-A, -B, and -C; and β 2 -microglobulin in human M14 and Namalva cells. The comparison was made on the basis of antiviral units, and the stimulation could be abolished by treatment of the interferon-γ preparation with pH 2 or anti-interferon-γ serum.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.40.1.172-176.1983

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