Affiliation:
1. Groupe de Recherche sur les Antimicrobiens et Microorganismes (GRAM), CHU de Rouen, Hôpital Charles Nicolle, 76031 Rouen Cedex, France
Abstract
ABSTRACT
Nasal surveillance cultures were performed for 54 patients exhibiting ≥10
3
CFU of methicillin-resistant coagulase-negative staphylococci per ml in central venous catheter (CVC) rinse cultures over a 6-month period. Forty-two of the nasal cultures yielded growth of methicillin-resistant coagulase-negative staphylococci, and 33 of the 42 cultures contained organisms that belonged to the same species as the CVC isolates. Of the 33 same-species isolates, 20 appeared to be identical strains by pulsed-field gel electrophoresis analysis. These data suggest that measures should be taken to reduce cross-contamination between the respiratory tract and intravascular devices. However, the potential interest in detecting methicillin-resistant coagulase-negative staphylococcus carriage in high-risk patients is hampered by the lack of sensitivity of nasal surveillance cultures.
Publisher
American Society for Microbiology
Cited by
17 articles.
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