Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2K b Offer New Options To Combat Cryptosporidiosis

Author:

Wang Yongli12,Gao Minghui1,Li Xiaoying3,Zhu Wenshuai1,Zhao Mengchun1,Li Jiayue1,Liu Xiaomeng14,Cao Letian3,Li Songrui3,Zhang Sumei3,Zhang Longxian3,Fan Shuhua14ORCID

Affiliation:

1. College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, People’s Republic of China

2. State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People’s Republic of China

3. College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People’s Republic of China

4. Institute of Neuroscience and Translational Medicine, Zhoukou Normal University, Zhoukou, People’s Republic of China

Abstract

Adaptive immune responses and T lymphocytes have been implicated as important mechanisms of parasite-induced protection. However, the role of CD8 + T lymphocytes in the resolution of C. parvum infection is largely unresolved.

Funder

河南省科学技术厅 | Henan Provincial Science and Technology Research Project

Education Department of Henan Province

Henan Province Foundation for University Key Teacher

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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