N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria-Reference-Cited by-同舟云学术

N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria

Published:2019-02-26 Issue:1 Volume:10 Page:
ISSN:2161-2129
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Newton Gerald L.¹,Rawat Mamta²

Affiliation:

1. Division of Biological Sciences, University of California, San Diego, San Diego, California, USA

2. Department of Biology, California State University—Fresno, Fresno, California, USA

Abstract

J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18 ) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum . In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S -adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria.

Funder

HHS | National Institutes of Health

National Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02634-18

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