Development and Evaluation of a Cryopreserved Whole-Parasite Vaccine in a Rodent Model of Blood-Stage Malaria

Author:

Stanisic Danielle I.1ORCID,Ho Mei-Fong1,Nevagi Reshma1,Cooper Emily1,Walton Maddison1,Islam Md Tanjir2,Hussein Waleed M.2,Skwarczynski Mariusz2,Toth Istvan234,Good Michael F.1

Affiliation:

1. Institute for Glycomics, Griffith University, Southport, Australia

2. School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Australia

3. School of Pharmacy, The University of Queensland, St Lucia, Australia

4. Institute for Molecular Bioscience, The University of Queensland, St Lucia, Australia

Abstract

Malaria is a mosquito-borne infectious disease that is caused by parasites of the genus, Plasmodium . There are seven different Plasmodium spp. that can cause malaria in humans, with P. falciparum causing the majority of the morbidity and mortality.

Funder

Medical Research Future Fund

Department of Health | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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