Interleukin-8 production by human mesothelial cells after direct stimulation with staphylococci

Author:

Visser C E1,Steenbergen J J1,Betjes M G1,Meijer S1,Arisz L1,Hoefsmit E C1,Krediet R T1,Beelen R H1

Affiliation:

1. Department of Cell Biology & Immunology, Faculty of Medicine, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.

Abstract

Mesothelial cells (MC) are able to produce interleukin-8 (IL-8) after stimulation with IL-1 beta or tumor necrosis factor alpha. The aim of our study was to investigate whether MC are able to produce IL-8 after direct stimulation with clinically relevant bacteria. We observed a significant IL-8 response by the MC which were directly stimulated with viable staphylococci.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference27 articles.

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