Interaction Between Analogue Resistance and Amino Acid Auxotrophy in Neurospora

Author:

Kinsey John A.1,Stadler David R.1

Affiliation:

1. Department of Genetics, University of Washington, Seattle, Washington 98105

Abstract

A new p -fluorophenylalanine resistant mutant of Neurospora ( fpr-1 ) was isolated. It is unaffected by the suppressor of a previously described resistance mutant, mtr . The fpr-1 locus is on linkage group V, tightly linked to act-2 . The expression of resistance to p -fluorophenylalanine by fpr-1 can be suppressed by genes controlling a requirement for lysine or arginine. The suppression seems to involve an increased sensitivity of the lysine and arginine auxotrophs to p -fluorophenylalanine.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference3 articles.

Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Recent Advances in Microbial Cell Growth Regulation Strategies for Metabolic Engineering;Biotechnology and Bioprocess Engineering;2020-12

2. References;The Neurospora Compendium;2001

3. Amino acid transport in eucaryotic microorganisms;Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes;1986-12

4. Biochemical genetics of Neurospora nuclease II: Mutagen sensitivity and other characteristics of the nuclease mutants;Genetical Research;1983-06

5. Chromosomal loci of Neurospora crassa;Microbiological Reviews;1982-12

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