Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression-Reference-Cited by-同舟云学术

Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Kim Wonyong¹^ORCID,Liu Rundong¹,Woo Sunmin²,Kang Kyo Bin²^ORCID,Park Hyun³,Yu Young Hyun⁴⁵,Ha Hyung-Ho⁴⁵,Oh Seung-Yoon⁶,Yang Ji Ho¹,Kim Hangun⁴⁵,Yun Sung-Hwan⁷,Hur Jae-Seoun¹^ORCID

Affiliation:

1. Korean Lichen Research Institute, Sunchon National University, Suncheon, South Korea

2. Research Institute of Pharmaceutical Sciences, College of Pharmacy, Sookmyung Women's University, Seoul, South Korea

3. Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, South Korea

4. College of Pharmacy, Sunchon National University, Suncheon, South Korea

5. Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, South Korea

6. Department of Biology and Chemistry, Changwon National University, Changwon, South Korea

7. Department of Medical Sciences, Soonchunhyang University, Asan, South Korea

Abstract

Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protection from biotic and abiotic stresses (e.g., herbivore attacks and UV irradiation).

Funder

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01111-21

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