CD55 Facilitates Immune Evasion by Borrelia crocidurae, an Agent of Relapsing Fever

Author:

Arora Gunjan1ORCID,Lynn Geoffrey E.1ORCID,Tang Xiaotian1,Rosen Connor E.2,Hoornstra Dieuwertje3ORCID,Sajid Andaleeb1,Hovius Joppe W.3,Palm Noah W.2,Ring Aaron M.2,Fikrig Erol1ORCID

Affiliation:

1. Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA

2. Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA

3. Amsterdam UMC, University of Amsterdam, Center for Experimental and Molecular Medicine, Amsterdam Infection and Immunity, Amsterdam, Netherlands

Abstract

Borreliaspecies are causative agents of Lyme disease and relapsing fever infections in humans.B. crociduraecauses one of the most prevalent relapsing fever infections in parts of West Africa. In the endemic regions,B. crociduraeis present in ~17% of the ticks and ~11% of the rodents that serve as reservoirs.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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