Reverse Genetic Assessment of the Roles Played by the Spike Protein and ORF3 in Porcine Epidemic Diarrhea Virus Pathogenicity-Reference-Cited by-同舟云学术

Reverse Genetic Assessment of the Roles Played by the Spike Protein and ORF3 in Porcine Epidemic Diarrhea Virus Pathogenicity

Published:2023-07-27 Issue:7 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Kristen-Burmann Claudia¹,Rogger Peter²³,Veiga Inês Berenguer²⁴,Riebesehl Stefanie¹,Rappe Julie²³,Ebert Nadine²³,Sautter Carmen A.²³,Kelly Jenna N.²,Stalder Hanspeter²³,Ehmann Rosina¹,Huber Michael⁵,Posthaus Horst⁴⁶,Ruggli Nicolas²³,Thiel Volker²³^ORCID,Tekes Gergely¹

Affiliation:

1. Institute of Virology, Justus Liebig University Giessen, Germany

2. Institute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland

3. Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland

4. Institute of Animal Pathology, Vetsuisse-Faculty, University of Bern, Switzerland

5. Institute of Medical Virology, University of Zürich, Switzerland

6. COMPATH, University of Bern, Switzerland

Abstract

PEDV is a swine pathogen that is responsible for significant animal and economic losses worldwide. Highly pathogenic variants can lead to a mortality rate of up to 100% in newborn piglets.

Funder

Federal Food Safety and Veterinary Office

Vetsuisse Faculty

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01964-22

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