Dietary Chitin Particles Called Mimetic Fungi Ameliorate Colitis in Toll-Like Receptor 2/CD14- and Sex-Dependent Manners-Reference-Cited by-同舟云学术

Dietary Chitin Particles Called Mimetic Fungi Ameliorate Colitis in Toll-Like Receptor 2/CD14- and Sex-Dependent Manners

Published:2019-05 Issue:5 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Louis Patricia¹,Mercer Brian²,Cirone Aiko M.¹,Brust Christina¹,Lee Zachary J.¹,Esiobu Nwadiuto²,Li Zhongwei¹,Wei Jianning¹,Dorey C. Kathleen³,Shibata Yoshimi¹,Nan Changlong¹

Affiliation:

1. Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA

2. College of Science, Florida Atlantic University, Boca Raton, Florida, USA

3. Virginia Tech Carilion School of Medicine, Virginia Tech, Roanoke, Virginia, USA

Abstract

Chitin is a natural N -acetylglucosamine polymer and a major structural component of fungal cell walls. Dietary chitin is mucoadhesive; anti-inflammatory effects of chitin microparticles (CMPs; 1- to 10-μm diameters) have been demonstrated in models of inflammatory bowel disease (IBD).

Funder

HHS | National Institutes of Health

U.S. Department of Defense

Florida Department of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00006-19

Reference61 articles.

1. Animal Models of Inflammatory Bowel Disease