Anti-LPS IgA and IgG Can Inhibit Serum Killing of Pseudomonas aeruginosa in Patients with Cystic Fibrosis-Reference-Cited by-同舟云学术

Anti-LPS IgA and IgG Can Inhibit Serum Killing of Pseudomonas aeruginosa in Patients with Cystic Fibrosis

Published:2021-11-16 Issue:12 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Pham Amy¹^ORCID,Ledger Emma L.¹,Coggon Carrie F.¹,Henderson Ian R.²^ORCID,Reid David W.³⁴⁵,Bell Scott C.⁴⁵⁶^ORCID,Smith Daniel J.⁴,Wells Timothy J.¹⁵^ORCID

Affiliation:

1. The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, QLD, Australia

2. Institute of Molecular Biology, The University of Queensland, Brisbane, QLD, Australia

3. QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia

4. The Adult Cystic Fibrosis Centre and Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, QLD, Australia

5. Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD, Australia

6. Children’s Health Research Centre, The University of Queensland, Brisbane, QLD, Australia

Abstract

Pseudomonas aeruginosa is one of the principal pathogens implicated in respiratory infections of patients with cystic fibrosis (CF) and non-CF bronchiectasis. Previously, we demonstrated that impaired serum-mediated killing of P. aeruginosa was associated with increased severity of respiratory infections in patients with non-CF bronchiectasis.

Funder

Department of Health, Australian Government | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00412-21

Reference36 articles.

1. Cystic fibrosis

2. Cystic Fibrosis Australia. Australian data registry. https://www.cysticfibrosis.org.au/dataregistry.

3. Managing Cystic Fibrosis