Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis-Reference-Cited by-同舟云学术

Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis

Published:2022-11-17 Issue:11 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Petronglo Jenna R.¹^ORCID,Putnam Nicole E.¹^ORCID,Ford Caleb A.²^ORCID,Cruz-Victorio Virginia³,Curry Jacob M.³^ORCID,Butrico Casey E.¹^ORCID,Fulbright Laura E.³,Johnson Joshua R.⁴⁵,Peck Sun H.⁴⁵^ORCID,Fatah Sana R.³^ORCID,Cassat James E.¹²³⁴⁶^ORCID

Affiliation:

1. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

2. Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA

3. Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA

4. Vanderbilt Center for Bone Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

5. Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA

6. Vanderbilt Institute for Infection, Immunology, and Inflammation (VI4), Vanderbilt University Medical Center, Nashville, Tennessee, USA

Abstract

Staphylococcus aureus is the major causative agent of bacterial osteomyelitis, an invasive infection of bone. Inflammation generated by the immune response to S. aureus contributes to bone damage by altering bone homeostasis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00417-22

Reference72 articles.

1. What is the Rate of Methicillin-resistant Staphylococcus aureus and Gram-negative Infections in Open Fractures?

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