Affiliation:
1. Research Laboratories, The Upjohn Company, Kalamazoo, Michigan
Abstract
Sebek, Oldrich
K. (The Upjohn Company, Kalamazoo, Mich.),
Lester M. Reineke, and Durey H. Peterson
. Intermediates in the metabolism of steroids by
Penicillium lilacinum
. J. Bacteriol.
83:
1327–1331. 1962—Nonproliferating cells of
Penicillium lilacinum
(Thom) metabolized progesterone successively to 20-β-hydroxy-4-pregnen-3-one, testosterone, androstenedione, and testololactone. Testosterone and androstenedione were readily interconvertible. 11-α-Hydroxyprogesterone was transformed in an analogous way and its intermediate, 11-α, 20-β-dihydroxy-4-pregnen-3-one, was isolated and identified by a combination of microbiological and chemical methods.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference11 articles.
1. Pathway of progesterone oxidation by Cladosporium resinae;FONKEN G. S.;J. Am. Chem. Soc.,1960
2. Mikrobielle Umwandlung von Steroiden. III. Direkte Umwandlung von Progesterone in Testosteron;HAN;Arzneimittel-Forsch.,1957
3. 20j3-Hydroxy-steroid-dehydrogenase;YBENER H. J.;II. Darstellung and Kristallisation. Biochem. Z.,1960
4. Formation of testosterone acetate by Saccharomyces fragilis;MCGUIRE J. S.;Biochim. et Biophys. Acta,1960
5. Oxygenation of steroids by Mucorales fungi;MURRAY H. C.;U. S. Patent,1952
Cited by
34 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献