Conconavalin A-stimulated bovine T-cell supernatants inhibit growth of Cowdria ruminantium in bovine endothelial cells in vitro

Author:

Mahan S M1,Smith G E1,Byrom B1

Affiliation:

1. University of Florida/U.S.A.I.D./SADC Heartwater Research Project, Harare, Zimbabwe.

Abstract

Conconavalin A-stimulated bovine T-cell supernatants inhibited the growth of Cowdria ruminantium in bovine endothelial cells in vitro but did not affect their entry. This finding represents one mechanism by which T cells may control C. ruminantium multiplication and hence affect the severity of disease.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference24 articles.

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2. Characterization of human cytotoxic Iymphocytes directed against cells infected with typhus group rickettsiae: evidence for Iymphokine effectors;Carl M.;J. Immunol.,1986

3. Lysis of cells infected with typhus group rickettsiae by human cytotoxic T cell clone;Carl M.;J. Immunol.,1987

4. Cloning, sequence, and expression of bovine interferon--y;Cerretti D. P.;J. Immunol.,1986

5. Techniques for the generation, cloning and characterization of bovine cytotoxic cells specific for the protozoan Theileria parva;Gooderis B. M.;J. Tissue Cult. Methods,1988

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