Reduced NR2F2 Expression in the Host Response to Infectious Bursal Disease Virus Infection Suppressed Viral Replication by Enhancing Type I Interferon Expression by Targeting SOCS5-Reference-Cited by-同舟云学术

Reduced NR2F2 Expression in the Host Response to Infectious Bursal Disease Virus Infection Suppressed Viral Replication by Enhancing Type I Interferon Expression by Targeting SOCS5

Published:2023-07-27 Issue:7 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

You Guangju¹²³,Li Wei¹²³,Wang Yongqiang¹²³,Cao Hong¹²³,Li Xiaoqi³,Gao Li¹²³,Zheng Shijun J.¹²³^ORCID

Affiliation:

1. National Key Laboratory of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China

2. Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, China

3. College of Veterinary Medicine, China Agricultural University, Beijing, China

Abstract

Infectious bursal disease (IBD) is an immunosuppressive disease causing considerable economic losses to the poultry industry worldwide. Nuclear receptors play an important role in regulating innate antiviral immunity.

Funder

MOST | National Natural Science Foundation of China

MOA | Earmarked Fund for Modern Agro-industry Technology Research System

MOST | National Key Research and Development Program of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00664-23

Reference72 articles.

1. Advances in vaccine research against economically important viral diseases of food animals: Infectious bursal disease virus

2. Infectious Bursal Disease Virus-Induced Immunosuppression in the Chick Is Associated with the Presence of Undifferentiated Follicles in the Recovering Bursa

3. Infectious bursal disease virus (IBDV) induces apoptosis in chicken B cells

4. Novel variants of infectious bursal disease virus can severely damage the bursa of fabricius of immunized chickens

5. An overview of infectious bursal disease

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