The Capsid Precursor Protein of Astrovirus VA1 Is Proteolytically Processed Intracellularly

Author:

Aguilera-Flores Catalina1,López Tomás1,Zamudio Fernando2,Sandoval-Jaime Carlos1,Pérez Edmundo I.3,López Susana1,DuBois Rebecca3ORCID,Arias Carlos F.1ORCID

Affiliation:

1. Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico

2. Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico

3. Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, USA

Abstract

Human astrovirus VA1 has been associated with neurological disease in immunocompromised patients. Its recent propagation in cell culture has facilitated the study of its biology.

Funder

Consejo Nacional de Ciencia y Tecnología

HHS | National Institutes of Health

UNAM | Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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