Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis-Reference-Cited by-同舟云学术

Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis

Published:2021-02-16 Issue:3 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Ni Chengpei¹,Gao Song¹²,Zheng Yuling¹,Liu Peng¹,Zhai Yajie³,Huang Wenhua¹,Jiang Hua¹,Lv Qingyu¹,Kong Decong¹,Jiang Yongqiang¹

Affiliation:

1. State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China

2. Department of Central Laboratory, Liaocheng People's Hospital, Liaocheng, Shandong Province, China

3. The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China

Abstract

Streptococcus suis serotype 2 is a crucial pathogenic cause of bacterial meningitis, a life-threatening disease with neurological sequelae and high rates of mortality. Inflammation triggered by S. suis infection must be precisely regulated to prevent further tissue damage.

Funder

National Key R&D Program of China

Chinese State Key Project Specialized for Infectious Disease

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00680-20

Reference49 articles.

1. Interaction of fibrinogen and muramidase-released protein promotes the development of Streptococcus suis meningitis