Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21-Reference-Cited by-同舟云学术

Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21

Published:1988-11 Issue:11 Volume:62 Page:4372-4375
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Reeves R H¹,O'Hara B F¹,Pavan W J¹,Gearhart J D¹,Haller O¹

Affiliation:

1. Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Abstract

A total of 318 progeny from four backcrosses involving different laboratory strains and subspecies of Mus musculus were analyzed to map the Mx gene to the region of mouse chromosome 16 (MMU 16) which is homologous to human chromosome 21 (HSA 21). This result suggests that Mx will be found in the region of HSA 21 which has been implicated in Down syndrome when inherited in three copies.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.62.11.4372-4375.1988

Reference26 articles.

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