The Protective Role of Interleukin 17A in Acinetobacter baumannii Pneumonia Is Associated with Candida albicans in the Airway-Reference-Cited by-同舟云学术

The Protective Role of Interleukin 17A in Acinetobacter baumannii Pneumonia Is Associated with Candida albicans in the Airway

Published:2023-01-24 Issue:1 Volume:91 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Tang Jiaxin¹^ORCID,Li Jiamin¹,Pan Jinqing¹,Shen Xiaoyuan¹,Ye Xiangsheng¹,Zhou Jiamin¹,Wang Ni¹,Xie Liang¹,Fuchs Beth Burgwyn²,Lionakis Michail S.³^ORCID,Mylonakis Eleftherios²^ORCID,Tan Xiaojiang¹^ORCID

Affiliation:

1. Department of Respiratory and Critical Care Medicine, Chronic Airways Diseases Laboratory, Huiqiao Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou, China

2. Department of Medicine, Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA

3. Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

Abstract

Recent studies have found that the coexistence of fungi and bacteria in the airway may increase the risk of infection, contribute to the development of pneumonia, and increase the severity of disease. Interleukin 17A (IL-17A) plays important roles in host resistance to bacterial and fungal infections.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00378-22

Reference50 articles.

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4. Candidaspp. airway colonization: A potential risk factor forAcinetobacter baumanniiventilator-associated pneumonia

5. Candida albicans Airway Colonization Facilitates Subsequent Acinetobacter baumannii Pneumonia in a Rat Model

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