Passive Immunization Against Experimental Pseudomonas Infection: Correlation of Protection to Verder and Evans “O” Serotypes

Author:

Bass Joseph A.1,McCoy John C.1

Affiliation:

1. The Shriners' Burns Institute, and the Department of Microbiology, The University of Texas Medical Branch, Galveston, Texas 77550

Abstract

Passive-protection tests were conducted in mice with antisera from rabbits immunized with formalinized or heat-killed cells or with an alcohol-precipitated fraction from the slime layer. Protection was conferred by antisera against the heatstable antigens and correlated well with agglutinin levels. Specificity was found to relate closely to the heat-stable “O” serotypes as defined by Verder and Evans.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference30 articles.

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1. Infection and immunity toPseudomonas;Clinical Reviews in Allergy;1991-03

2. Infection and Immunity to Pseudomonas;Cystic Fibrosis;1990

3. Effects of a Glycopolypeptide from the Slime of P. aeruginosa on Phagocytosis by Mouse Macrophages;Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale. A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie;1983-07

4. Immunization against Pseudomonas aeruginosa: The effects of serotype and virulence in mouse protection tests;Journal of Biological Standardization;1982-01

5. Protective effects of S-sulfonated human gamma globulin against experimental infections in mice;Infection and Immunity;1980-11

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