Influence of rodent malaria on the course of Leishmania enriettii infection of hamsters

Author:

Belehu A,Poulter L W,Turk J L

Abstract

Plasmodium yoelii infection was established in hamsters, and the effect of this type of malaria on concurrent Leishmania enriettii infection was examined. It was found that the course of the L. enriettii infection was affected by P. yoelii and that this effect depended on the relative timing of the two infections. A chronic malarial infection with Plasmodium berghei was also established in hamsters, and this was found to affect the course of a concurrent L. enriettii infection in a similar manner to P. yoelii. These results are discussed in relation to current knowledge of the immunosuppressive effects of plasmodia.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference21 articles.

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2. Establishment of cutaneous Leishmania enriettii infection in hamsters;Belehu A.;Infect. Immun.,1976

3. Studies on the immunology and serology of leishmaniasis. VIII. The identity of strains of Leishmania from Ethiopian diffuse cutaneous leishmaniasis;Bray R. S.;Trans. R. Soc. Trop. Med. Hyg.,1969

4. Experimental cutaneous leishmaniasis. IV. Selective suppression of cell-mediated immunity during the response of guinea pigs to infection with Leishmania enriettii;Bryceson A. D. M.;Clin. Exp. Immunol.,1974

5. Immunity in cutaneous leishmaniasis of the guinea pig;Bryceson A. D. M.;Clin. Exp. Immunol.,1970

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