Emergence in France of Multiple Clones of Clinical Streptococcus pneumoniae Isolates with High-Level Resistance to Amoxicillin-Reference-Cited by-同舟云学术

Emergence in France of Multiple Clones of Clinical Streptococcus pneumoniae Isolates with High-Level Resistance to Amoxicillin

Published:1999-06 Issue:6 Volume:43 Page:1480-1483
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Doit Catherine¹,Loukil Chawki¹,Fitoussi Frederic¹,Geslin Pierre²,Bingen Edouard¹

Affiliation:

1. Laboratoire de Microbiologie, Hôpital Robert Debré, 75019 Paris,1 and

2. Centre National de Référence du Pneumocoque, Centre Hospitalier de Créteil, 94010 Créteil,2 France

Abstract

ABSTRACT The genetic relatedness of French isolates of Streptococcus pneumoniae highly resistant to amoxicillin (MIC, ≥4 μg/ml, equal to or exceeding those of penicillin) was investigated by molecular fingerprinting. The results suggest that high-level resistance to amoxicillin has emerged within preexisting penicillin-resistant clones.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.43.6.1480

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