Development of a Multiplexed Assay for Detection of Leishmania donovani and Leishmania infantum Protein Biomarkers in Urine Samples of Patients with Visceral Leishmaniasis-Reference-Cited by-同舟云学术

Development of a Multiplexed Assay for Detection of Leishmania donovani and Leishmania infantum Protein Biomarkers in Urine Samples of Patients with Visceral Leishmaniasis

Published:2019-05 Issue:5 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Abeijon Claudia¹,Alves Fabiana²,Monnerat Severine²,Wasunna Monique³,Mbui Jane³,Viana Agostinho G.⁴,Bueno Lilian L.⁴,Siqueira Williane F.⁴,Carvalho Silvio G.⁵,Agrawal Neha⁶,Fujiwara Ricardo⁴,Sundar Shyam⁷,Campos-Neto Antonio¹⁸^ORCID

Affiliation:

1. DetectoGen Inc., Grafton, Massachusetts, USA

2. Drugs for Neglected Diseases Initiative, Geneva, Switzerland

3. KEMRI Centre for Clinical Research, Nairobi, Kenya

4. Federal University of Minas Gerais, Belo Horizonte, MG, Brazil

5. State University of Montes Claros, Montes Claros, MG, Brazil

6. Temple University, Philadelphia, Pennsylvania, USA

7. Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

8. Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts, USA

Abstract

Visceral leishmaniasis (VL) is a serious and fatal disease caused by the parasites Leishmania infantum and Leishmania donovani . The gold standard diagnostic test for VL is the demonstration of parasites or their DNA in spleen, lymph node, or bone marrow aspirates.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02076-18

Reference40 articles.

1. –;WHO;Wkly Epidemiol Rec,2018

2. Leishmaniasis Worldwide and Global Estimates of Its Incidence

3. Predictors of Visceral Leishmaniasis Relapse in HIV-Infected Patients: A Systematic Review