Resistance of Pseudomonas aeruginosa to Imipenem Induced by Eluates from Siliconized Latex Urinary Catheters Is Related to Outer Membrane Protein Alterations-Reference-Cited by-同舟云学术

Resistance of Pseudomonas aeruginosa to Imipenem Induced by Eluates from Siliconized Latex Urinary Catheters Is Related to Outer Membrane Protein Alterations

Published:1999-02 Issue:2 Volume:43 Page:397-399
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Martínez-Martínez Luis¹,Pascual Alvaro¹,del Carmen Conejo María¹,Picabea Leandro²,Perea Evelio J.¹

Affiliation:

1. Department of Microbiology, School of Medicine, University of Seville,1 and

2. Forensic Science Institute,2 Seville, Spain

Abstract

ABSTRACT The activity of imipenem against Pseudomonas aeruginosa HUS-3 decreased by 16 times in the presence of substances eluted from siliconized latex urinary catheters (SLUCs). SLUCs did not inactivate imipenem or increase β-lactamase activity. The outer membrane of P. aeruginosa HUS-3 grown in the presence of eluate lacked an OprD-like protein and expressed a new 50-kDa protein. The decreased activity of imipenem against P. aeruginosa in the presence of SLUCs is related to the loss of an OprD-like protein and the expression of a new outer membrane protein.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.43.2.397

Reference23 articles.

1. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding.;Bradford M. M.;Anal. Biochem.,1976

2. A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria

3. New norfloxacin resistance gene in Pseudomonas aeruginosa PAO

4. Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa.;Köhler T.;Mol. Microbiol.,1997

5. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.;Laemmli U. K.;Nature (London),1970

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