Asymptomatic Leprosy Infection among Blood Donors May Predict Disease Development and Suggests a Potential Mode of Transmission

Author:

Goulart Isabela Maria Bernardes,Araujo Sergio,Filho Adilson Botelho,de Paiva Paulo Henrique Ribeiro,Goulart Luiz Ricardo

Abstract

Blood donor samples (1,007) were assessed for anti-phenolic glycolipid 1 (PGL-1) IgM antibodies andMycobacterium lepraeDNA presence, which had 3.8% and 0.3% positivity, respectively. After a 5-year follow-up period, six individuals with positive markers developed leprosy, raising the hypothesis that asymptomatic infection among blood donors may be an undisclosed mode of leprosy transmission via transfusion.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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