A CUC triplet confers leucine-dependent regulation of the Bacillus subtilis ilv-leu operon-Reference-Cited by-同舟云学术

A CUC triplet confers leucine-dependent regulation of the Bacillus subtilis ilv-leu operon

Published:1996-04 Issue:7 Volume:178 Page:2150-2153
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Marta P T¹,Ladner R D¹,Grandoni J A¹

Affiliation:

1. Department of Molecular Biology, University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Stratford, New Jersey 08084, USA.

Abstract

Regulation of the ilv-leu operon probably involves interaction of a tR NA(GAG) with leader region mRNA. Conversion of a CUC (Leu) triplet located within the leader region to UUC (Phe), CGC (Arg), or UAC (Tyr) converted reporter gene expression to control by corresponding amino acids. Conversion of the CUC triplet to CUU (Leu) decreased expression and disrupted regulation. The results suggested that other tRNAs can substitute for tRNA(Leu) but that interactions in addition to pairing of the anticodon with the CUC triplet are important for proper control.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.178.7.2150-2153.1996

Reference16 articles.

1. Clustering and co-transcription of the Bacillus subtilis genes encoding the aminoacyl-tRNA synthetases specific for glutamate and for cysteine and the first enzyme for cysteine biosynthesis;Gagnon Y.;J. Biol. Chem.,1993

2. Mutations in the gene for a tRNA that functions as a regulator of transcriptional attenuation in Bacillus subtilis;Garrity D.;Genetics,1994

3. The Bacillus subtilis ochre suppressor sup-3 is located in an operon of seven tRNA genes;Garrity D. B.;J. Bacteriol.,1994

4. Regions of the Bacillus subtilis ilv-leu operon involved in regulation by leucine;Grandoni J. A.;J. Bacteriol.,1993

5. Transcriptional regulation of the ilv-leu operon of Bacillus subtilis;Grandoni J. A.;J. Bacteriol.,1992

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