PET Imaging of Translocator Protein as a Marker of Malaria-Associated Lung Inflammation-Reference-Cited by-同舟云学术

PET Imaging of Translocator Protein as a Marker of Malaria-Associated Lung Inflammation

Published:2021-09-16 Issue:10 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Goggi Julian L.¹^ORCID,Claser Carla²³,Hartimath Siddesh V.¹,Hor Pei Xiang⁴,Tan Peng Wen¹,Ramasamy Boominathan¹,Abdul Rahman Husaini¹,Cheng Peter¹,Chang Zi Wei²⁴,Nguee Samantha Yee Teng⁴,Tang Jun Rong¹,Robins Edward G.¹⁵,Renia Laurent²⁴

Affiliation:

1. Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore

2. Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore

3. Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil

4. A*STAR Infectious Diseases Laboratories, Agency for Science, Technology and Research (A*STAR), Singapore

5. Clinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

Abstract

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a severe complication of malaria that occurs despite effective antimalarial treatment. Currently, noninvasive imaging procedures such as chest X-rays are used to assess edema in established MA-ARDS, but earlier detection methods are needed to reduce morbidity and mortality.

Funder

Agency for Science, Technology and Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00024-21

Reference41 articles.

1. WHO Global Malaria Programme. 30 November 2020. World malaria report 2020. World Health Organization, Geneva, Switzerland.

2. Immunological processes in malaria pathogenesis

3. Cerebral malaria