Bex, the Bacillus subtilis Homolog of the Essential Escherichia coli GTPase Era, Is Required for Normal Cell Division and Spore Formation-Reference-Cited by-同舟云学术

Bex, the Bacillus subtilis Homolog of the Essential Escherichia coli GTPase Era, Is Required for Normal Cell Division and Spore Formation

Published:2002-11-15 Issue:22 Volume:184 Page:6389-6394
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Minkovsky Natalie¹,Zarimani Arash²,Chary Vasant K.¹,Johnstone Brian H.²,Powell Bradford S.³,Torrance Pamela D.²,Court Donald L.³,Simons Robert W.²,Piggot Patrick J.¹

Affiliation:

1. Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140

2. Department of Microbiology, Immunology and Molecular Genetics, University of California at Los Angeles, Los Angeles, California 90095

3. Gene Regulation and Chromosome Biology Laboratory, Division of Basic Sciences, National Cancer Institute at Frederick, Frederick, Maryland 21702

Abstract

ABSTRACT The Bacillus subtilis bex gene complemented the defect in an Escherichia coli era mutant. The Bex protein showed 39% identity and 67% similarity to the E. coli Era GTPase. In contrast to era , bex was not essential in all strains. bex mutant cells were elongated and filled with diffuse nucleoid material. They grew slowly and exhibited severely impaired spore formation.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.184.22.6389-6394.2002

Reference42 articles.

1. Ahnn, J., P. E. March, H. E. Takiff, and M. Inouye. 1986. A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins. Proc. Natl. Acad. Sci. USA83:8849-8853.

2. Anderson, P. E., J. Matsunaga, E. L. Simons, and R. W. Simons. 1996. Structure and regulation of the Salmonella typhimurium rnc-era-recO operon. Biochimie78:1025-1034.

3. Arigoni, F., F. Talabot, M. Peitsch, M. D. Edgerton, E. Meldrum, E. Allet, R. Fish, T. Jamotte, M.-L. Curchod, and H. Loferer. 1998. A genome-based approach for the identification of essential bacterial genes. Nat. Biotechnol.16:851-856.

4. Britton, R. A., B. S. Powell, S. Dasgupta, Q. Sun, W. Margolin, J. R. Lupski, and D. L. Court. 1998. Cell cycle arrest in Era GTPase mutants: a potential growth rate-regulated checkpoint in Escherichia coli. Mol. Microbiol.27:739-750.

5. Axial filament formation in Bacillus subtilis: induction of nucleoids of increasing length after addition of chloramphenicol to exponential-phase cultures approaching stationary phase

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Nucleic acid-binding KH domain proteins influence a spectrum of biological pathways including as part of membrane-localized complexes;Journal of Structural Biology: X;2024-12

2. GTPase Era at the heart of ribosome assembly;Frontiers in Molecular Biosciences;2023-10-04

3. Era, a GTPase-like protein of the Ras family, does not control ribosome assembly in Mycobacterium tuberculosis;Microbiology;2022-08-02

4. The (p)ppGpp-binding GTPase Era promotes rRNA processing and cold adaptation in Staphylococcus aureus;PLOS Genetics;2019-08-29

5. Role of Era in assembly and homeostasis of the ribosomal small subunit;Nucleic Acids Research;2019-07-02