Diagnosis of American trypanosomiasis (Chagas' disease) by the new complement fixation test

Author:

Garcia E1,Ramirez L E1,Monteon V1,Sotelo J1

Affiliation:

1. National Institute of Neurology and Neurosurgery of Mexico, Mexico City.

Abstract

A new immunodiagnostic method of complement fixation was used for serodiagnosis of American trypanosomiasis; 92% sensitivity and 99% specificity were obtained, for an overall accuracy of 97%. This test can be used in field studies, obviating the use of most laboratory equipment and imported reagents; places where economic limitations hinder the use of other immunodiagnostic procedures; and in association with other tests for confirmation of the diagnosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference12 articles.

1. Camargo M. E. 1988. American trypanosomiasis (Chagas' disease) p. 744-753. In A. Balows W. J. Hausler Jr. and E. H. Lennette (ed.) Laboratory diagnosis of infectious diseases: principles and practice vol. 1. Springer-Verlag New York.

2. Chagas' disease diagnosis: evaluation of several tests in blood bank screening;Carvalho M. R.;Transfusion,1993

3. Chiari E. and E. P. Camargo. 1984. Culturing and cloning T. cruzi p. 23-27. In C. M. Morel (ed.) Genes and antigens of parasites laboratory manual 2nd ed. World Health Organization Rio de Janeiro Brazil.

4. Serological screening for Trypanosoma cruzi among blood donors in central Brazil;de Andrade A. L.;Bol. Oficina Sanit. Panam.,1992

5. A new complement fixation test for the diagnosis of neurocysticercosis in cerebrospinal fluid;Garcia E.;J. Neurol.,1991

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