Molecular characterization of common treponemal antigens

Author:

Hanff P A,Miller J N,Lovett M A

Abstract

A molecular characterization of cross-reactive antigens of Treponema pallidum Nichols and Treponema phagedenis biotype Reiter that are reactive with normal and syphilitic human sera is described. At least 8 common polypeptides, 14 T. pallidum-specific antigens, and 2 T. phagedenis biotype Reiter-specific antigens were identified.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference33 articles.

1. Purification of Treponema pallidum from infected rabbit tissue: resolution into two treponemal populations;Baseman J. B.;Infect. Immun.,1974

2. Purification and characterization of axial filaments from Treponema phagedenis biotype reiterii (the Reiter treponeme);Bharier M.;J. Bacteriol.,1974

3. The demonstration of a common antigen in Reiter's treponeme and virulent Treponema pallidum;Cannefax G. R.;J. Immunol.,1959

4. Studies on the antigenic structure of Treponema pallidum. 3. Antigenic properties of polysaccharides isolated from Reiter's apathogenic strain;Christiansen A. A.;Acta Pathol. Microbiol. Scand.,1962

5. Isolation and purification of the protein antigen of the Reiter treponeme;D'Alessandro G.;Am. J. Syph. Gonorrhea Vener. Dis.,1953

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