Median infective dose of Treponema pallidum determined in a highly susceptible guinea pig strain-Reference-Cited by-同舟云学术

Median infective dose of Treponema pallidum determined in a highly susceptible guinea pig strain

Published:1991-01 Issue:1 Volume:59 Page:453-456
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wicher K¹,Wicher V¹

Affiliation:

1. Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509.

Abstract

The median infective dose of Treponema pallidum subsp. pallidum and the production of immunity to reinfection in C4D guinea pigs have been determined with 10(1) to 10(6) organisms per infective dose. The mean infective dose is 10(2) organisms, and immunity--in those animals that demonstrated lesions--developed after 4.5 months postinfection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.59.1.453-456.1991

Reference25 articles.

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