SARS-CoV-2 E Gene Variant Alters Analytical Sensitivity Characteristics of Viral Detection Using a Commercial Reverse Transcription-PCR Assay-Reference-Cited by-同舟云学术

SARS-CoV-2 E Gene Variant Alters Analytical Sensitivity Characteristics of Viral Detection Using a Commercial Reverse Transcription-PCR Assay

Published:2021-06-18 Issue:7 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Tahan Stephen¹^ORCID,Parikh Bijal A.²^ORCID,Droit Lindsay¹²,Wallace Meghan A.²,Burnham Carey-Ann D.¹²³⁴^ORCID,Wang David¹²^ORCID

Affiliation:

1. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA

2. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

3. Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA

4. Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

Abstract

Diagnostic assays for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are essential for patient management, infection prevention, and the public health response for coronavirus disease 2019 (COVID-19). The efficacy and reliability of these assays are of paramount importance in both tracking and controlling the spread of the virus.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00075-21

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