Erythema Multiforme Caused by Treponema pallidum in a Young Patient with Human Immunodeficiency Virus Infection

Author:

Chiang Mei-Chun1,Chiang Fu-Chiang2,Chang Yun-Ting23,Chen Te-Li13,Fung Chang-Phone13

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

2. Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan

3. School of Medicine, National Yang-Ming University, Taipei, Taiwan

Abstract

ABSTRACT Erythema multiforme (EM) is usually caused by drug reactions or virus infection. We report a case of secondary syphilis presenting as EM in an HIV-infected patient, proved by immunohistochemical staining, which is rare in the literature. It is valuable to determine the etiology of EM to optimize treatment.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference14 articles.

1. Al-Johani, K. A., S. Fedele, and S. R. Porter. 2007. Erythema multiforme and related disorders. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 103 : 642-654.

2. Auquier-Dunant, A., M. Mockenhaupt, L. Naldi, O. Correia, W. Schroder, and J. C. Roujeau. 2002. Correlations between clinical patterns and causes of erythema multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis: results of an international prospective study. Arch. Dermatol. 138 : 1019-1024.

3. Behrhof, W., E. Springer, W. Brauninger, C. J. Kirkpatrick, and A. Weber. 2008. PCR testing for Treponema pallidum in paraffin-embedded skin biopsy specimens: test design and impact on the diagnosis of syphilis. J. Clin. Pathol. 61 : 390-395.

4. Coopman, S. A., R. A. Johnson, R. Platt, and R. S. Stern. 1993. Cutaneous disease and drug reactions in HIV infection. N. Engl. J. Med. 328 : 1670-1674.

5. Dylewski, J., and M. Duong. 2007. The rash of secondary syphilis. CMAJ 176 : 33-35.

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