Affiliation:
1. Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA
Abstract
ABSTRACT
Analysis of global temporal gene expression by human intestinal cells when exposed to
Lactobacillus acidophilus
revealed induction of immune-related pathways and NF-κB target genes after a 1-h exposure, compared to a 4- or 8-h exposure. Additionally, an
L. acidophilus
derivative expressing covalently bound flagellin resulted in increased induction of
il8
,
cxc1
, and
cxcl2
compared to the parent
L. acidophilus
.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
15 articles.
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