Susceptibility of Multidrug-Resistant Gram-Negative Urine Isolates to Oral Antibiotics-Reference-Cited by-同舟云学术

Susceptibility of Multidrug-Resistant Gram-Negative Urine Isolates to Oral Antibiotics

Published:2016-05 Issue:5 Volume:60 Page:3138-3140
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hirsch Elizabeth B.¹²,Zucchi Paola C.¹,Chen Alice¹,Raux Brian R.¹,Kirby James E.²³,McCoy Christopher²,Eliopoulos George M.²³

Affiliation:

1. Northeastern University, Boston, Massachusetts, USA

2. Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

3. Harvard Medical School, Boston, Massachusetts, USA

Abstract

ABSTRACT Increasing resistance among Gram-negative uropathogens limits treatment options, and susceptibility data for multidrug-resistant isolates are limited. We assessed the activity of five oral agents against 91 multidrug-resistant Gram-negative urine isolates that were collected from emergency department/hospitalized patients. Fosfomycin and nitrofurantoin were most active (>75% susceptibility). Susceptibilities to sulfamethoxazole-trimethoprim, ciprofloxacin, and ampicillin were ≤40%; empirical use of these agents likely provides inadequate coverage in areas with a high prevalence of multidrug-resistant uropathogens.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02961-15

Reference15 articles.

1. Increasing Antimicrobial Resistance and the Management of Uncomplicated Community-Acquired Urinary Tract Infections

2. Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000–2009)

3. The epidemiology of urinary tract infection

4. The emerging threat of multidrug-resistant Gram-negative bacteria in urology

5. Incidence of Antibiotic-Resistant Escherichia coli Bacteriuria According to Age and Location of Onset: A Population-Based Study From Olmsted County, Minnesota

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Carbapenem-Resistant Enterobacteriaceae in Urinary Tract Infections: From Biological Insights to Emerging Therapeutic Alternatives;Medicina;2024-01-26

2. An insight into genes responsible for fosfomycin resistance among uropathogens of asymptomatic bacteriuria during pregnancy: A North Indian study;Access Microbiology;2023-12-01

3. Characterization of bioactive compound isolated from Micromonospora marina KPMS1 and its activity against emerging antibiotics resistant strains of Klebsiella pneumoniae HAUTI7 and Proteus vulgaris HAUTI14;International Journal of Biological Macromolecules;2023-10

4. Prevalence and characteristics of multidrug-resistant Escherichia coli sequence type ST131 at two academic centers in Boston and Minneapolis, USA;American Journal of Infection Control;2023-04

5. The Five Ds of Outpatient Antibiotic Stewardship for Urinary Tract Infections;Clinical Microbiology Reviews;2021-12-15