Affiliation:
1. Communicable Disease Center, U.S. Public Health Service, Atlanta, Georgia
Abstract
Kaufman, Leo
(Communicable Disease Center, Atlanta, Ga.),
and Sharon Blumer
. Occurrence of serotypes among
Histoplasma capsulatum
strains. J. Bacteriol.
91:
1434–1439. 1966.—Extensive studies with a fluorescent antibody specific for the yeast form of
Histoplasma capsulatum
indicated that, although most strains of
H. capsulatum
stained intensely, others stained weakly and some did not stain. These observations suggested that antigenic variants of the fungus existed. To test this hypothesis, reciprocal cross-staining and adsorption procedures were performed with fluorescein-labeled antiglobulins to four strains of
H. capsulatum
. Fifty-six strains of
H. capsulatum
and 11 strains of
H. duboisii
were studied. The data indicate that at least five serotypes of
H. capsulatum
occur. One is closely related antigenically to
H. duboisii
and
Blastomyces dermatitidis
.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
45 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献