Development of Two Mouse Models for Vaccine Evaluation against Cryptosporidiosis-Reference-Cited by-同舟云学术

Development of Two Mouse Models for Vaccine Evaluation against Cryptosporidiosis

Published:2022-07-21 Issue:7 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Dayao Denise Ann¹^ORCID,Jaskiewcz Justyna¹²,Lee Sangun¹^ORCID,Oliveira Bruno Cesar¹³,Sheoran Abhineet¹,Widmer Giovanni¹,Tzipori Saul¹

Affiliation:

1. Department of Infectious Disease and Global Health; Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, USA

2. Center for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children, Boston, Massachusetts, USA

3. União das Faculdades dos Grandes Lagos, São José do Rio Preto, Brazil

Abstract

Cryptosporidiosis was shown a decade ago to be a major contributor to morbidity and mortality of diarrheal disease in children in low-income countries. A serious obstacle to develop and evaluate immunogens and vaccines to control this disease is the lack of well-characterized immunocompetent rodent models.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00127-22

Reference42 articles.

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2. CRYPTOSPORIDIUM PARVUM IN CHILDREN WITH DIARRHEA IN MULAGO HOSPITAL, KAMPALA, UGANDA

3. Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study

4. Epidemiology of Cryptosporidiosis in France from 2017 to 2019

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