Eosinophils and Macrophages within the Th2-Induced Granuloma: Balancing Killing and Healing in a Tight Space

Author:

Ariyaratne Anupama1,Finney Constance A. M.1ORCID

Affiliation:

1. Department of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada

Abstract

Granuloma formation is a key host immune response generated to confine invading pathogens and limit extensive host damage. It consists of an accumulation of host immune cells around a pathogen. This host response has been extensively studied in the context of inflammatory diseases. However, there is much less known about Th2-type granulomas generated in response to parasitic worms.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Canada Foundation for Innovation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference188 articles.

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