The HIF-1α/LC3-II Axis Impacts Fungal Immunity in Human Macrophages-Reference-Cited by-同舟云学术

The HIF-1α/LC3-II Axis Impacts Fungal Immunity in Human Macrophages

Published:2019-07 Issue:7 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Friedrich Dirk¹^ORCID,Zapf Dorinja¹,Lohse Björn¹,Fecher Roger A.²³,Deepe George S.²,Rupp Jan¹⁴^ORCID

Affiliation:

1. Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany

2. Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

3. Division of Immunobiology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA

4. German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany

Abstract

The fungal pathogen Histoplasma capsulatum causes a spectrum of disease, ranging from local pulmonary infection to disseminated disease. The organism seeks residence in macrophages, which are permissive for its survival.

Funder

HHS | National Institutes of Health

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00125-19

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