Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions

Author:

Mergenhagen Kari A.1,Wattengel Bethany A.1,Skelly Megan K.1,Clark Collin M.1,Russo Thomas A.23ORCID

Affiliation:

1. Department of Pharmacy, Veterans Affairs Western New York Healthcare System, Buffalo, New York, USA

2. Division of Infectious Diseases, Veterans Affairs Western New York Healthcare System, Buffalo, New York, USA

3. Department of Medicine, University at Buffalo, Buffalo, New York, USA

Abstract

Many antibiotics carry caution stickers that warn against alcohol consumption. Data regarding concurrent use are sparse. An awareness of data that address this common clinical scenario is important so health care professionals can make informed clinical decisions and address questions in an evidence-based manner. The purpose of this systematic review was to determine the evidence behind alcohol warnings issued for many common antimicrobials.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference124 articles.

1. Do antibiotics and alcohol mix? The beliefs of genitourinary clinic attendees

2. Trends in Prescription Drug Use Among Adults in the United States From 1999-2012

3. Centers for Disease Control and Prevention. 2016. Outpatient antibiotic prescriptions—United States, 2016. Centers for Disease Control and Prevention, Atlanta, GA.

4. National Institute on Alcohol Abuse and Alcoholism. 2014. Harmful interactions mixing alcohol with medicines. NIH publication no. 13-5329. National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD.

5. U.S. Food and Drug Administration. 2013. Avoid food-drug interactions. U.S. Food and Drug Administration White Oak MD.

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